RAF Typhoon fighter aircraft have operated alongside French aircraft in a joint strike against an subterranean weapons facility in Syrian territory employed by the IS group, according to the UK's MoD.
The facility, identified by reconnaissance, was believed to be storing arms and explosives, the release indicated, and was situated in hills just north of the historic site of Palmyra in the heart of Syria.
"Our aircraft employed Paveway IV guided bombs to hit a several access tunnels down to the depot... early reports indicate the objective was successfully hit," officials stated.
There was no indication of any harm to civilians in the strike on Saturday evening and every plane involved returned safely, the defence officials confirmed.
The British jets were supported by a Voyager refuelling tanker.
Daesh - alternatively referred to as the so-called Islamic State - enforced extremist governance over large swathes of both Syria and Iraq until 2019.
"This action demonstrates the UK's leading role, and determination to stand shoulder to shoulder with allied nations, to eliminate any re-emergence of IS and their harmful and extremist ideologies in the area," the British Defence Secretary the Defence Secretary stated.
RAF aircraft have performed overwatch operations over Syrian airspace to "forestall any efforts to regroup" of Islamic State subsequent to its military defeat at the battle of Baghuz in 2019, the MoD reported.
"I must thank the personnel of British forces participating in this operation for their skill and their courage," Healey said. "Including them were a great many UK service members deployed over the holidays. This operation, to eliminate dangerous terrorists who endanger our way of life, demonstrates how our armed forces are always on standby, all year round, ensuring Britain's security at home and strong abroad."
In December, the United States armed forces carried out what it described as a "major assault" targeting IS targets in Syria, subsequent to an ambush resulted in the deaths of two US troops and a local interpreter in the Palmyra area.
The U.N. says Islamic State still has an estimated 5,000 to 7,000 militants in Syria and Iraq.